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Mucosal immunity Currently licensed SARS-CoV-2 vaccines are all delivered parenterally via intramuscular injection, which leads to some limitations for vaccine roll-out and potentially for protective efficacy (Table 1)
Reconstituted solutions should be clear and colorless
Impurities or bacteria in an IV product can be dangerous
In UK practice, monitoring is primarily based on clinical response rather than routine blood tests, as post-treatment serum B12 measurements can be misleadingly high and may not reflect tissue levels
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