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The trade-off is that reconstitution adds a preparation step
Some patients experience mild fatigue, headache, or water retention as the body adjusts
Contraindications : Individuals allergic to cobalt or any other ingredient in the injection should avoid B12 injections
[12] Use is contraindicated in individuals with a known hypersensitivity to tretinoin, azelaic acid, niacinamide, or any excipient, and in those with active eczematous dermatitis or facial sunburn until healing occurs
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