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Selective Targeting of TP53-Y220C Mutant AML By PC14586 Results in TP53 Wild-Type Conformation and Synergistical Apoptosis Induction By Concomitant Inhibition of Xpo-1, MDM2, or Bcl-2
Not approved by the FDA or any regulatory authority
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2019), platinum ions entering mitochondria can bind to mitochondrial DNA (mtDNA) to form stable platinum-mtDNA adducts (Darwish et al
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