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The review documented GSHs broad roles including antioxidant defence, nutrient metabolism, gene expression, DNA and protein synthesis, cell proliferation and apoptosis, signal transduction, cytokine production, immune response, and protein glutathionylation

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It has been reported that GSTP interacts with JNK, TRAF2, and STAT3 and involves in protecting cells against apoptosis, oxidative stress, and angiotensin II stimulation ( Sepsis, a systemic inflammatory response induced by aggressive infection, is a leading cause of death in intensive care units associated with significant public healthcare problem ( Immune cells recognize not only microorganisms (pathogen-associated molecular patterns

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