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Neuropsychiatric monitoring is particularly important: Mood changes : Report any worsening depression, increased anxiety, or suicidal thoughts immediately Sleep disturbances : Both medications can affect sleep patterns Fatigue or dizziness : May impair ability to drive or operate machinery Serotonin syndrome : A rare but serious condition associated with SSRIs, especially when combined with other serotonergic medications (not related to semaglutide) Metabolic and other considerations : Blood glucose effects : Wegovy can affect blood glucose levels
In other cases, uncontrollable cravings for unhealthy, calorie-dense foods can drive people to eat too many calories for their bodys energy needs
doi: 10.3389/fnhum.2022.838692 59 WangL
In a post hoc analysis of the STEP 5 trial, in adults without diabetes and with a BMI 30 kg/m 2 or 27 kg/m 2 with 1 weight-related comorbidity, a greater proportion of patients treated with once-weekly subcutaneous semaglutide 2.4 mg achieved remission of metabolic syndrome, and fewer developed incident metabolic syndrome, compared with placebo
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