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The administration of MTX is linked to an enhanced generation of ROS, which cause oxidative damage to cellular components and disrupt redox homeostasis (Schmidt et al

GHK-Cu is posited to possibly boost the expression and nuclear translocation of Nrf2 in lung tissues, thereby promoting the transcription of genes that combat oxidative stress and possibly enhancing the cellular resilience against oxidative damage

Liposomal forms show superior bioavailability in recent studies, with absorption rates up to 90% higher than standard capsules