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Employees of companies that provide coverage for Medicare Advantage programs will have access to GLP-1 drugs for obesity, but their physicians will have to navigate a prior authorization program
The mechanism involves increased insulin resistance at the cellular level and enhanced hepatic gluconeogenesis
Nature Chemical Biology
These can help contextualize whether a patient's glucose dysregulation is primarily insulin-resistant (favoring metformin first) or beta-celllimited (where GLP-1 may be more central)
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