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International Journal of Experimental Medicine 14:13644.[PubMed] , [Google Scholar])

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117 Additionally, MAPK pathway hyperactivation, driven by NF1 loss, induces ligand-independent ER activation through persistent RAS signaling, contributing to endocrine resistance

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Food and Drug Administration (FDA) recommends using FDA-approved semaglutide products, like Wegovy, Ozempic, or Rybelsus, whenever possible

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In this study, the greater treatment persistence and comparable adherence of semaglutide QW versus these other GLP-1 RAs may be a result of the associated clinical benefits of semaglutide QW such as improved glycemic control and greater weight loss [21, 25]

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