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Compared with tirzepatide, Wegovy (semaglutide) 2.4 mg showed a significant 57% greater reduction in the risk of heart attack, stroke or death from any cause, in people with overweight or obesity and cardiovascular disease (CVD) while on treatment 1 Similarly, the study showed a significant 29% reduction in the risk for heart attack, stroke and death from any cause in the Wegovy users compared with tirzepatide users in all treated people, regardless of any gaps in their treatment 1 The findings support growing evidence that the established CV benefit seen with Wegovy is specific to the semaglutide molecule and therefore cannot be generalized to the GLP-1 or GIP/GLP-1-receptor agonist classes 1 -- Novo Nordisk presented data from the STEER real-world study of evidence gathered from actual patient experiences at the European Society of Cardiology (ESC) Congress 2025 in Madrid, Spain

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GLP-1 medications help by: Stabilizing Blood Sugar Swings: Fewer highs and lows mean smaller inflammatory surges

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