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CYP450 oxidation activity followed a similar pattern as GSH initial concentration and production rate, with the normalized number of zonal necrosed cells increasing from 2.2 times at 20% zonation to 13.2 times at 80% zonation

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The experiment evaluated the effects of varying glutathione concentration, peroxide concentration, and incubation time on GPx activity, as the modified GPx-DTNB assay measured