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Iodine treatment in obese mice showed a weight-reducing effect and modified the gut microbiota, leading to an increase in pathogenic bacteria and a decrease in beneficial bacteria

Symptoms of Frozen Shoulder The main symptoms of frozen shoulder include: Dull or aching pain in the shoulder Stiffness and limited range of motion Pain that worsens at night, affecting sleep Frozen shoulder typically progresses through three stages: Freezing stage (6-9 months): Pain gradually increases, and shoulder movement becomes limited

Repeatedly using the same injection site can lead to skin irritation, tissue damage, and even scar formation

Nevertheless, these effects on gonadal structure and sperm quality were partially lost after administration of GLP-1R antagonist exendin (9-39), thus suggesting that dapagliflozin may protect against diabetes-induced spermatogenic dysfunction via GLP-1R/PI3K/Akt-dependent pathway [165]