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It improves insulin sensitivity, activates AMPK (a longevity pathway similar to caloric restriction), reduces inflammation, and may extend lifespan through multiple mechanisms
Clinicians also prescribe the drugs for weight loss in people without type 2 diabetes
Semaglutide has a prolonged half-life of approximately one week, allowing for once-weekly subcutaneous administration in its injectable forms
The authors identified future areas of investigation including male models, long-term treatment effects, and combination with other NAD+ precursors such as NMN
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