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The authors concluded that the nutraceutical collagen peptides had positive effects on skin structure, and this supplementation could induce regeneration of collagen fibers in human skin [47]

This effect was attributed to the inhibition of the Shh signaling pathway, leading to the suppression of Shh and Bcl-2 expression, inhibition of the nuclear translocation of Gli1, and increase of caspase-3 cleavage 20 (Figure 1)

Fact: Higher doses do not matter if your body cannot absorb them