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In this trial, CSF samples were taken, showing that the drug was able to cross the BBB and that 12 weeks after the trial had stopped, there was no drug present in the CSF anymore
a separate treatment-use formulation (0.5 mg and 1.0 mg base per vial, for treating growth hormone deficiency and growth failure in children) was approved September 26, 1997 under NDA 20-443
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