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The medication's primary gastrointestinal side effectsparticularly nausea, vomiting, and diarrheacan lead to dehydration if fluid intake is inadequate or losses are not appropriately replaced
To date, this poor oral bioavailability 2 has meant that peptides have been administered parenterally (ie, via intravenous injection)
Glucagon-like peptide 1: a potent glycogenic hormone
Within the cytosol, long-chain FAs are converted into acyl-CoA esters, while short- and medium-chain FAs diffuse into the mitochondrial matrix and are converted into acyl-CoA esters 3,6,7
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