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To dissect the role of caspases in the observed profile, we included two inhibitors: Q-VD-OPh (referred to hereafter as QVD), a pan-caspase inhibitor targeting caspases 1, 3, 7, 8, 9, 10 and 12, and Ac-DEVD-CHO (referred to hereafter as DEVD), which selectively inhibits caspases 3, 6, 7, 8 and 10
One study on patients with major depressive disorder compared patients with hyperphagic versus hypophagic symptoms with healthy controls, finding differential effects of ghrelin depending on somatic symptom profile (Cerit et al., 2019)
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