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While surveying the literature in preparation of this manuscript we have also noticed and reported an increasing interest in the role that GSTs play in neurodegeneration, where isozymes belonging to the family may be either up-regulated, mutated or absent, according to the different diseases
These are not the same thing, and understanding the difference changes how you evaluate the formulation
Patients experiencing significant GI symptoms may attribute their mood changes to the medication itself rather than to the secondary effects of physical discomfort
Notably, tirzepatide showed more robust improvements in triglycerides and liver fat, suggesting broader metabolic benefits
