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Miyazaki T, Chung S, Sakai H, Ohata H, Obata Y, Shiokawa D, et al

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The observation that the metabolic effects of GLP-1RA/tesaglitazar depend on functional GLP-1R in vivo align with our in vitro demonstration that GLP-1RA/tesaglitazar fails to induce PPAR/RXR heterodimerization in the absence of GLP-1R (Fig