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Consequently, the GSH deprotonation step was considered non-rate-determining and thermodynamically favoured, leading us to use the GSH-thiolate as the starting point to compute the reaction mechanism for the conversion of flav-3-on-4-ol ( 7 ) into cyanidin ( 8-B4 ) in the wild-type enzyme and the C13S variant (Extended Data Fig
Proc 37, 10741075
Alzheimer disease, in StatPearls treasure (Island, FL: StatPearls Publishing)
The subsequent targeted analysis was performed on a broad panel of metabolites, enabling independent evaluation of pathway-level signals across analytical platforms
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