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According to NICE guidance (NG28), GLP-1 receptor agonists like Ozempic are typically considered for people with type 2 diabetes who have inadequate glycaemic control despite treatment with metformin and other oral medications, or when other treatment options are contraindicated or not tolerated

Victoza (liraglutide), the first GLP-1 for type 2 diabetes to lose exclusivity in June 2024, may not generate significant savings due to its once-daily dosing and limited market share

Obesity is defined in adults as a body mass index over 30

Like Notch signaling components, levels of osteopontin protein and gene expression are positively correlated with NAFLD disease severity and extent of fibrosis (202)