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Subsequent investigations demonstrated that FSP1, regulated by Nrf2, significantly inhibited lung cancer cell growth and sensitised Keap1 -deficient cells to ferroptosis by knockdown or inhibition of FSP1 expression in Keap1 post-mutant lung cancer [46, 78]
H.BlochO.Zelnic-YuvalD.LoveI.Mendel-CohenL.FlorH.et al (2018)
Dehydration from gastrointestinal side effects, as noted in FDA Medication Guides, may contribute substantially to headache development, especially during the initial treatment period when these effects are most pronounced
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