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Theoretical and route-specific risks FDA's 2024 review specifically flagged that no published human exposure data exists for the subcutaneous, transdermal, or intranasal routes that compounding pharmacies have offered

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Comparative studies in obese mice showed that AOD-9604 produced slightly greater fat reduction than the unmodified fragment at equivalent doses

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Research suggests this may be due to higher concentrations of beta-3 adrenergic receptors in these fat depots

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