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Forty animals with fasting blood glucose higher than 11.1 mmol/L and body weight ranging from 28.9 to 36.0 g were randomly divided into control group, MET group (0.26 g/kg), low-dose DTE group (DTE-L, 0.78 g/kg) and high-dose DTE group (DTE-H, 1.56 g/kg), with 10 animals in each group
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