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Pretreatment with 5 M curcumin in human dermal fibroblasts (HDFs) significantly downregulates caspase-3 and upregulates anti-apoptotic Bcl-2, preserving cellular integrity under UVA stress (Liu et al., 2018)
Both peptides demonstrated strong ACE-inhibitory activity, with IC values of 0.92 mol/L for TTP and 3.4 mol/L for gAgAP
Pineal peptides do not have the extensive clinical trial data that pharmaceutical sleep aids do
At the same time, GHK-Cu increases the production of extracellular matrix proteins, such as collagen and elastin
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