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Safety and limitations: Topical L-carnitine is usually well tolerated, but sensitive skin may experience adverse reactions such as erythema and itching
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Some considerations and risks of long-term use include metabolic effects that could be changes in insulin sensitivity and cardiovascular effects that could shift blood pressure or lipid levels in vulnerable individuals
[53] The trials were conducted at 673 sites in 24 countries, including Argentina, Australia, Brazil, Canada, India, Israel, Japan, Mexico, Russian Federation, South Korea, Taiwan, European Union, and the United States (including Puerto Rico)
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