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Advantages of secretagogues in research: a more physiological hormonal profile, activation of the complete axis (GH + IGF-1 + IGFBP-3), and intact negative feedback that limits supraphysiological effects
Besides diet-induced obesity, PQQ ameliorates programing obesity of the offspring through maternal supplementation and alters gut microbiota, which reduces obesity risk
Human Data : Limited clinical studies report favorable safety, with no severe adverse effects noted
doi:10.1080/15287399409531852
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