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NICE guidance (NG69) advises against offering medication as the sole treatment for eating disorders
We defined psychiatric comorbidity as having alcohol and substance abuse (ICD-10: F10-F19), schizophrenia (ICD-10: F20-F29), bipolar disorders (ICD-10: F30-F31), major depression (ICD-10: F32-F33), eating disorders (ICD-10: F50), personality disorders (ICD-10: F60-F62) and psychotropics within 10 years prior to index date ( See Supplementary Table 1)
Despite the availability of pharmacological treatments, these interventions fail to prevent disease progression due to their limited ability to penetrate the blood-brain barrier (BBB) and systemic side effects
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