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The theory is that long-term use of semaglutide, particularly without a controlled diet, could lead to vitamin B12 deficiency due to the effects on gastric emptying
Orforglipron might also find a place as a follow-on treatment for people who started their weight management with injectable semaglutide
This is the question most patients actually open with
10.1016/j.bbamem.2012.07.032 87 SchelshornD.JolyF.MutelS.HampeC.BretonB.MutelV.et al (2012)
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