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This mechanism reduces appetite and calorie intake but does not directly affect muscle metabolism or creatine uptake

"Sermorelin stimulates physiologic GH pulses, improving muscle recovery, connective tissue repair, and sleep quality critical elements of recovery and rehabilitation in both athletic and aging populations." Schmid et al., Neuroendocrinology Clinical Evidence Clinical studies have demonstrated that Sermorelin effectively increases GH and IGF-1, leading to improvements in lean body mass, sleep quality, and overall recovery capacity

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Antidepressants like mirtazapine, mood stabilizers like olanzapine, and certain antiseizure drugs can drive weight gain