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Conversely, loss of FGF21 increases both liver and plasma cytokine levels in mice, including TNF, IL-6, and MCP-1, upon chronic alcohol exposure (181)
PubMed PMID: 20143256
These agonists directly activate the GLP-1R in hepatocytes and help alleviate hepatic steatosis through signaling pathways and genes involved in lipid metabolism
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