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Rare cases of intestinal obstruction and acute kidney injury (associated with dehydration) have been reported in post-marketing surveillance
The replacement of Ala8 with Aib did not significantly change the binding affinity, but did result in a decline in potency as a substrate for DPP4
Through a comprehensive retrospective analysis of the strength of the association, analogy, and consistency metrics of GLP-1RAs and SSIBs, we concluded that there was no evidence reasonably suggesting an association between GLP-1RAs and SSIBs
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