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A systematic review and meta-analysis of randomized-controlled trials

Photo (Extrinsic) Aging Extrinsic or photoaging plays a major role in damaging the skin, which is due to the exposure to the ultraviolet (UV) rays of the sun that activate the same cascade of events (seen in chronological aging) but to a much greater extent [10, 18]

30 , 31 HIGH-ENERGY RADIATION, OXIDATION, SMOKING, AND FAILURE OF PRIMARY AND SECONDARY DEFENSE SYSTEMS Only a brief introduction to some of these topics is offered here