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While a study in chronic insomnia patients has reported that short-term DSIP administration is unlikely to be of major therapeutic benefit, a 16-month study in mice found that long-term DSIP administration increased maximum life span and decreased the rate of tumor growth [22, 23]

However, these uncontrolled observations require validation through prospective, controlled clinical trials before establishing standard treatment durations for specific clinical indications

Tumours stained and quantified for TOM20 intensity ( a ) or cleaved Caspase 3 positivity ( b )

In research, BPC-157 and GHK-Cu are often studied together to explore their synergistic effects