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There are two compartment-specific BCAA transaminases in humans, BCAT1 (or cBCAT), which is located in the cytoplasm and primarily expressed in the brain, and BCAT2 (or mBCAT), which is located in mitochondria with ubiquitous expression

Children with this condition may develop dark-colored spots on the mouth, lips, eyes, nose, hands, and feet

Dermatologists recommend using glutathione with sunscreen to prevent sun damage

Recognizing Lean Liver Disease in Clinical Practice Clinicians should consider metabolic liver disease in patients who present with: Normal BMI but central adiposity (increased waist circumference) Mildly elevated liver enzymes without a clear cause Dyslipidemia or insulin resistance features Fatty liver on incidental imaging Routine use of noninvasive tests such as FIB4, ELF score, or transient elastography can help stratify risk and guide hepatology referrals