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Cavallini G, Ferraretti AP, Gianaroli L, Biagiotti G, Vitali G
On a molecular basis, the TRPA1 (Transient receptor potential ankyrin subtype 1) ion channels in nociceptors allow the release of calcitonin gene-related peptide (CGRP) from dural afferents upon activation, mediating neurogenic inflammation, and migraine behavioral picture in animal models (25)
therefore, it is speculated that the degree of arterial calcification may be related to the high concentration of TMAO (60)
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