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It is plausible that betaine supplementation promotes athletic performance by maintaining cellular hydration and reducing homocysteine levels, thereby encouraging healthy cardiovascular function and blood flow [16]
Published clinical research has characterised the compound in controlled trials: a Phase 2 obesity trial reported dose-dependent body-weight change in the study population (Jastreboff et al., 2023), and a separate Phase 2 trial investigated the GIP/GLP-1/glucagon agonist in people with type 2 diabetes (Rosenstock et al., 2023)
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