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Eligibility and contraindications Each of these medications comes with eligibility criteria, but these drugs are generally indicated for: Adults who have obesity (BMI of 30 or above) Adults who have overweight (BMI of 27 or above) as well as a weight-related comorbid condition, such as high blood pressure, type 2 diabetes, and obstructive sleep apnea Some groups of people should not take these medications, including: People who are pregnant People with a personal or family history of medullary thyroid cancer People who have a known serious hypersensitivity to the ingredients in the medication Additionally, you should not use these medications in combination or with other weight loss medications
Formulated only with EWG green grade ingredients
No direct retatrutide-versus-tirzepatide randomised controlled trial has been published or announced as of April 2026
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