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For example, the SPARC level increased in the skeletal muscles of young male subjects after 11 weeks of a strength-training program [21], and it transiently increased in the serum of young healthy men immediately after a single bout of cycling [22]

Copper peptide GHK-Cu is a tripeptide with copper core studied for collagen synthesis and tissue remodeling

Overall, proper oral administration may support systemic and gut-specific repair effectively, while localized injections or intravenous therapy is more suitable for targeted musculoskeletal issues

For example, tirzepatide, a dual GLP-1/GIP agonist, has shown promising results in NASH trials