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In addition, miR-223-3p has been shown to reduce hippocampal neuronal injury and ameliorate anxiety- and depression-like behaviors through inhibition of NLRP3 signaling [105], while miR-129-5p mitigates the cognitive impairment by inhibiting neuroinflammation and maintaining astrocytic glutamate uptake in a frontotemporal dementia model [106]
FOXO4-DRI has been studied in preclinical models examining selective elimination of these cells
Research Insights DSIP is a small peptide composed of nine amino acids, making it a nonapeptide ( 10 )
Antigen-specific peptide therapies that induce immune tolerance to myelin proteins represent perhaps the most elegant approach to MS treatment
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