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Cagrilintide (NN00739) is a synthetic analog of amylin , a hormone released with insulin that promotes satiety and slows gastric emptying
qPCR was performed using Master Mix Select SYBR (Applied Biosystems) and QuantStudio 7 Flex Real-Time PCR System (Applied Biosystems)
Phase 2 trial (NEJM, 2023) The landmark Phase 2 trial, published in the New England Journal of Medicine, randomized 338 adults with obesity to receive weekly subcutaneous retatrutide at doses of 1 mg, 4 mg, 8 mg, or 12 mg, or placebo, for 48 weeks
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