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Among the passage routes of drugs via nasal mucosa, large molecules like peptides, proteins, and nucleic acids are often reported to cross the nasal epithelium following the transcellular pathway or endocytosis (Illum, 2003

it exports fat and bile from the liver which is responsible for seeing exported fat and burning it for energy and fuel

However, the allergenicity can be overcome due to the treatment of BP with specific enzymes such as pectinase, papain, and cellulase

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