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Additional investigations such as vitamin D, B12, thyroid function, or creatine kinase levels may be considered based on clinical presentation
He is a board-certified dermatologist with a special interest in dermatologic conditions that result from cancer treatments.
ME/CFS and Genetics: Chronic Fatigue Syndrome Genes, Immune Pathways, and Natural SolutionsGenetic variants in immune, mitochondrial, and inflammatory pathways (NK cells, NLRP3, interferon, complement, TRP channels) increase ME/CFS susceptibility
Summary: Feeling worse after a B12 injection typically reflects your body adjusting to replenished vitamin levels, triggering metabolic processes that may temporarily cause fatigue, headaches, or injection site discomfort
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