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The optimal formulation was obtained by continuous sonication at 100% amplitude for 45 minutes, conditions which led to 600 nm crystals with 0.521 polydispersion index and fast drug dissolution
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And for the people who push through, the discomfort often leads to skipped doses, slower titration schedules, and ultimately, diminished results
Common side effects include: Nausea and vomiting Diarrhoea or constipation Reduced appetite Abdominal discomfort or bloating Injection site reactions (redness, itching, or mild swelling) These effects can often be managed by eating smaller, lower-fat meals, avoiding lying down immediately after eating, staying well hydrated, and adhering to the gradual dose-escalation schedule
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