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Administration of spironolactone, a selective MR antagonist, counteracted stress-induced mGlu2 suppression and the related development of depressive-like behavior, implicating rapid action of glucocorticoids via a receptor that is known to modulate glutamate release [20]

Results can be long-lasting with consistent habits

In Zepbound clinical trials, patients lost an average of 20% of their body weight.* Learn more about potential side effects Zepbound is a dual-action GLP-1/GIP medication called tirzepatide that may be prescribed for weight loss, if appropriate

Novo Nordisk says it supports a health care system that ensures patient access and affordability