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This timeline matches B12 pharmacokinetics: intramuscular methylcobalamin reaches peak serum concentration at 8-12 hours, but tissue saturation (particularly in the liver and nervous system) occurs over 48-72 hours as the vitamin is transported into cells and converted to active coenzyme forms (Andrs et al., 2018)

She presents it as less likely than many supplements to cause nausea

Although the exemplified procedures herein illustrate the practice of the present invention in some of its embodiments, the procedures should not be construed as limiting the scope of the invention

Clark-Loeser adamantly emphasizes, Sun exposure! Additionally, she says you shouldnt use hydroquinone while taking or applying any medications that may increase your sensitivity to the sun