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TB-500 is the acetylated heptapeptide fragment Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln, corresponding to residues 17-23 of native human thymosin 4 (43 amino acids)
clarified this dilemma by using CRISPR-Cas9 to introduce the risk variant, a non-risk control, and a PTPN22 knockout into human cord blood-derived nave T cells from the same donor
Extended storage: Refrigerate at 2-8C if storing beyond 6 months
By interfering with the interaction between FOXO4 and another protein called p53, the researchers developed a compound called FOXO4-DRI, which specifically targets FOXO4
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