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Consistently, the expression of NF-B target genes ( IL6 , IL11 , ADAM8 , and IRAK2 (supplementary Fig
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placebo in adults with overweight or obesity without diabetes (STEP 3), mean body weight decreased 16.0% with semaglutide compared with 5.7% with placebo, both as adjunct to intensive behavioral therapy (ETD 10.3%
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