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GLP-1 RISKS (with risk increases) Gastrointestinal Nausea and vomiting: 30% higher GERD (acid reflux): 14% higher Gastritis: 10% higher Noninfectious gastroenteritis: 12% higher Gastroparesis: 7% higher Diverticulosis/diverticulitis: 8% higher Drug-induced pancreatitis: 146% higher Other Systems Hypotension (low blood pressure): 6% higher Syncope (fainting): 6% higher Sleep disturbances: 12% higher Headaches: 10% higher Arthritis: 11% higher Joint pain: 11% higher Tendinitis/synovitis: 10% higher Kidney stones: 15% higher Interstitial nephritis: 6% higher This approach allowed researchers to evaluate the medications effects across 175 different health outcomes everything from heart attacks to headaches
The starting dose (0.25 mg semaglutide or 2.5 mg tirzepatide) is a titration dose, not a therapeutic dose
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