Inhalation methods, such as chasing the dragon, are associated with leukoencephalopathy, characterized by progressive motor and cognitive impairments, ataxia, and spastic paresis (Keogh et al., 2003)

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PubMed Marso, S.P., Bain, S.C., Consoli, A., Eliaschewitz, F.G., Jdar, E., Leiter, L.A., et al
Thats what showed results in studies