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They found that topical application directly to the skin every day for seven days in an emollient cream resulted in a clear reduction in disease compared to untreated animals, and their findings were confirmed using PASI (Psoriasis Area and Severity Index) scoring, which is used in clinical practice to measure the extent and severity of psoriasis

6b), MB07811, a liver-targeted TR agonist could enhance insulin secretion and reduce glucose levels independent of weight loss in non-obese mice (Fig